Developing Novel Plant-Inspired Treatments for Parkinson’s Disease
Time: 10:45 am
day: Day Two Track A AM
Details:
- Identifying proprietary Minimum essential mixtures (MEM) from Cannabis extracts using a serially-reductionist approach, screening in silico, cell, and animal models of Parkinson’s disease
- Cell-based studies identified novel complex mixtures of 8-12 Cannabis ingredients with both significant neuroprotective potential and the ability to increase dopamine secretion
- Animal-based studies demonstrated that our simplified MEM containing three cannabinoids each significantly reduced Parkinsonian movement symptoms elicited using 6-OHDA
- Our MEM for the treatment of Parkinson’s motor symptoms are being developed for their first-in-human trials by incorporation into Oral Dissolving Tablets which enhance drug delivery and patient compliance
