Justine Manos

Justine Manos

Company: Abbvie Inc.

Job title: Principal Scientist II, Tau Pathobiology


Human in vitro Disease Modeling – Development of Firstin- Class iPSC Models of Endogenous Tau Aggregation 11:15 am

Optimization and QC of a well-known differentiation protocol improve robustness and reproducibility Development of tau seeding models using AD brain-derived or recombinant tau seeds demonstrates that successful templating of endogenous tau requires compatibility between neuronal tau and exogenous seeds In vitro endogenous tau aggregation is neuron subtype-specific, mimicking selective vulnerability observed in ADRead more

day: Day One Track A AM

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