Overcoming the Lack of Functional Homology Conservation in Inflammatory Genes Across Mice, Monkeys & Humans to Enhance Model Recapitulations
Time: 11:00 am
day: Conference Day One - Track Two
Details:
- Addressing cross-species differences in inflammatory gene function, microglial response to stimuli, and how vasculature regulates neuroinflammation
- Exploring strategies to overcome these variances to enhance the translational value of in vivo studies of neuroinflammation in AD and PD
- Reviewing streamlined differentiation approaches to generate iPSC-derived microglia from patient-derived cells
