Manuela Polydoro
Company: Muna Therapeutics
Job title: Vice President, Head of Translational Medicine
Seminars:
Panel Discussion: What is Still Not Understood About the Role of Inflammation in Alzheimer’s & Parkinson’s? 12:00 pm
How can we overcome cross-model differences in neuroinflammation to develop more translatable targets? What are the latest understandings of the roles of microglia and astrocytes in AD and PD pathology? What is still unknown? What is currently understood from preclinical studies about the possible peripheral immune component?Read more
day: Conference Day Two - Track Two
Overcoming the Lack of Functional Homology Conservation in Inflammatory Genes Across Mice, Monkeys & Humans to Enhance Model Recapitulations 11:00 am
Addressing cross-species differences in inflammatory gene function, microglial response to stimuli, and how vasculature regulates neuroinflammation Exploring strategies to overcome these variances to enhance the translational value of in vivo studies of neuroinflammation in AD and PD Reviewing streamlined differentiation approaches to generate iPSC-derived microglia from patient-derived cellsRead more
day: Conference Day One - Track Two
Presenter Q+A & Audience Discussion 12:00 pm
day: Conference Day One - Track Two