Developing a Reliable Mouse Model to Better Understand and Predict ARIA-E and ARIA-H Observed in Subjects Treated with Anti-Aβ Immunotherapy: Myth or Reality?
Time: 8:00 am
day: Conference Day One
Details:
- Risk factors for the occurrence of ARIA in patients treated with Abeta immunotherapy are being elucidated, but pathogenic mechanisms involved in ARIA remain hypothetical
- Deciphering these pathogenic mechanisms, or defining features of new molecules that would prevent the occurrence of ARIA remain a priority for the field
- Basic research effort is needed to develop reliable models that will be used to investigate the mechanistic hypotheses and test potential treatments
