Roundtable Discussion: Leveraging Real-World Add-On Therapy Templates to Advance Combination Strategies in Neurodegenerative Diseases

2:00 pm - Wednesday 4th February 2026

  • Criteria for selecting patient subgroups most likely to benefit from multi-mechanism approaches (e.g., stage of disease, biomarker profiles)
  • Prioritizing clinically meaningful primary endpoints and complementary secondary measures to capture additive or synergistic effects
  • Using established PD add-on protocols and emerging AD combination trials as models for endpoint selection and regulatory alignment

Speakers:

Regulatory Science Lead
UCB