Identifying Protective Variants for Alzheimer’s & Parkinson’s with the UK BioBank, Using Next Generation Sequencing (NGS) as a Major Source for Target Discovery
Time: 11:00 am
day: Discovery Track AM
Details:
- Harnessing whole exome and whole genome sequencing to identify protective/rare variants and their subsequent prioritization
- Exploring the influence of causal variants in the context of mutations in the rest of the genome (epistasis and penetrance)
- Identifying subgroups on the basis of comorbidities and diagnosis using examples from the UK Biobank
