Mining Patient Resiliency-Associated Targets for Novel Antibody Therapeutics: Discovery of the CD33 antibody, ATLX-1088
Time: 11:30 am
day: Discovery Track AM
Details:
- Sequencing the B cell repertoire from resilient patient populations to look for protective auto-antibodies in an unbiased manner
- Identifying resilient autoantibodies to uncover novel targets and pathways for target discovery
- Harnessing the neuroprotective activity of microglia within the 1088 program as a novel antibody therapeutic