Restoring Endo-Lysosomal Function: Translational Biomarkers to Accelerate Parkinson’s Therapeutics
3:30 pm - Tuesday 3rd February 2026
- Discovering metabolomic and lipidomic signatures of endolysosomal dysfunction in PD patients and healthy controls to define disease-relevant biomarker baselines
- Validating pharmacodynamic biomarkers via small molecule target manipulation in cell and patient-derived samples to track treatment effects early in the pipeline
- Accelerating drug discovery by using these biomarkers to derisk candidate selection, inform dose selection, and shorten time to clinical proof-of-concept in Parkinson’s
